Obesity May Accelerate the Aging Process

Aging in the atherosclerosis milieu may accelerate the consumption of bone marrow endothelial progenitor cells.

OBJECTIVE We have demonstrated that bone marrow cells from young and wild-type (WT), but not old apoE-/-, mice are capable of preventing atherosclerosis. This study was performed to elucidate the numerical and functional changes underlying the efficacy difference between young and old bone marrow. METHODS AND RESULTS CD34+/VEGFR2+ conventional endothelial progenitor cells and lin-/cKit+/Sca-1...

Accelerate DMAIC using Process Mining

Process mining is an accessible technique to visualize and analyze process variation and yield improvements. We experienced that Process Mining can help to overcome some of the barriers of the Six Sigma DMAIC cycle in improvement projects. This results in a significant acceleration to complete such a cycle.

Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage.

Inadequate dietary intakes of vitamins and minerals are widespread, most likely due to excessive consumption of energy-rich, micronutrient-poor, refined food. Inadequate intakes may result in chronic metabolic disruption, including mitochondrial decay. Deficiencies in many micronutrients cause DNA damage, such as chromosome breaks, in cultured human cells or in vivo. Some of these deficiencies ...

[The aging process].

Cocoa administration may accelerate orthodontic tooth movement by inducing osteoclastogenesis in rats

Objective(s): To investigate the effect of cocoa on orthodontic tooth movement (OTM) rate, osteoprotegerin (OPG), and receptor activator of nuclear factor κ β ligand (RANKL) levels after OTM.Materials and Methods: A total of 24 Sprague-Dawley rats were included in the study. They were equally divided into two groups: cocoa and control. The upper incisors of all rats were subjected to 35 cN orth...